Author Topic: What is the mechanism of action of Tadacip 20 Mg ?  (Read 7 times)

kirazmattson

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What is the mechanism of action of Tadacip 20 Mg ?
« on: April 26, 2024, 07:22:35 AM »

Tadacip 20 Mg contains the active ingredient tadalafil, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. The mechanism of action of Tadacip 20 Mg involves its effects on the enzyme PDE5 and the cyclic guanosine monophosphate (cGMP) pathway in the body. Here's how it works:

Relaxation of Smooth Muscles: In the erectile tissue of the penis, sexual stimulation triggers the release of nitric oxide (NO). Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), which acts as a signaling molecule in the smooth muscle cells of the penile arteries and corpus cavernosum (erectile tissue). cGMP causes the smooth muscles to relax, allowing blood to flow into the penis and produce an erection.
Inhibition of PDE5: Phosphodiesterase type 5 (PDE5) is an enzyme that breaks down cGMP, leading to a decrease in its levels and the relaxation of smooth muscle cells. Tadalafil, the active ingredient in Tadacip 20 Mg, inhibits the action of PDE5, allowing cGMP to accumulate and exert its effects on smooth muscle relaxation more effectively.
Enhanced Blood Flow to the Penis: By inhibiting PDE5, tadalafil prolongs the action of cGMP, leading to sustained relaxation of the smooth muscles in the penile arteries and corpus cavernosum. This results in increased blood flow to the penis, which helps produce and maintain an erection sufficient for sexual activity.
Extended Duration of Action: Tadalafil has a longer duration of action compared to other PDE5 inhibitors, such as sildenafil and vardenafil. This allows for greater flexibility in the timing of sexual activity, as Tadacip 20 Mg can be taken on an as-needed basis and its effects can last for up to 36 hours.
In summary, Tadacip 20 Mg works by inhibiting the enzyme PDE5, which allows for the accumulation of cGMP in the smooth muscle cells of the penis. This leads to relaxation of the smooth muscles and increased blood flow to the penis, resulting in improved erectile function and the ability to achieve and maintain erections during sexual activity.