ABBREVIATIONS TAM, tamoxifen; 4 OH TAM, 4 hydroxytamoxifen; 4 OH N desmethyl TAM, 4 hydroxy N desmethyl tamoxifen endoxifen; UGT, UDP glucuronosyltransferase; UDPGA, UDP glucuronic acid; DMEM, Dulbecco s modified Eagle s medium; BCA, bicinchoninic acid; PCR, polymerase chain reaction; SDM, site directed mutagenesis; HEK, human embryonic kidney; LC MS, liquid chromatography mass spectrometry; MS, mass spectrometric; HPLC, high pressure liquid chromatography; DMSO, dimethyl sulfoxide; HLM, human liver microsome; Std, standard
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