stromectol generic name VEGF binding to VEGF receptor 2 VEGFR 2 initiates a tyrosine kinase signaling cascade that stimulates the production of factors that variously stimulate vessel permeability epithelial nitric oxide synthase; eNOS, proliferation survival bFGF; basic fibroblast growth factor, migration intercellular adhesion molecules ICAMs; vascular cell adhesion molecules VCAMs; matrix metalloproteases MMPs and finally differentiation into mature blood vessels
