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It is uncertain as to how the lack of IL-15 receptor affects the immune system, but shows that EBV infection does have some profound effects on how the immune system and more, and it does not take a far stretch of imagination to see how decreased maturation of NK cells leads to a weakened response to further, reccurring EBV episodes, or even persistent infections with the bacteria chlamydophila pneumoniae, as chlamydophila pneumoniae is an intracellular pathogen as well.