In certain embodiments a formulation is provided wherein the formulation is prepared by lyophilizing about 300 400 mg, about 350 400 mg, or about 360 380 mg, or more particularly about 373 mg, of Compound 1 Pattern 1 dihydrochloride, dihydrate, about 50 100, about 60 80, or more particularly about 76 mg citric acid monohydrate, and about 250 350 mg, about 280 320 mg or more particularly about 300 mg of mannitol, and optionally sodium hydroxide and or hydrochloric acid to adjust the pH as desired
stromectol demodex
