<a href=http://tamoxifenolvadex.com/>will nolvadex raise testosterone</a> The first-line treatment for PCOS has been lifestyle interventions; however, major clinical features such as acne, hirsutism, menstrual irregularities, and anovulation require pharmacological treatment that includes contraceptives, such as COC and progestin-only contraceptives, and infertility drugs, such as letrozole or clomiphene, metformin, and spironolactone.