Would you be able to reword your question I m not entirely sure I understand, but I ll take a crack at it correct me if I m answering a question you weren t asking.
difference between doxycycline hyclate and monohydrate The evidence for the involvement of this enzyme in the injury is compelling 1 there was a marked release of pro- MMP- 2 during reperfusion, 2 there was a negative correlation between pro- MMP- 2 release during reperfusion and functional recovery of hearts subjected to increasing duration of ischemia, 3 infusion of semipurified MMP- 2 worsened the recovery of function after ischemia and reperfusion, 4 there was a positive correlation between the ability of the MMP inhibitor doxycycline to improve the recovery of mechanical function and its ability to inhibit myocardial MMP- 2 activity, and 5 there was a protective effect of a neutralizing antibody to MMP- 2 in ischemic- reperfused hearts.