Solvents that find use in the preparation of endoxifen according to the present invention include but are not limited to tetrahydrofuran, dichloromethane, chloroform, 1, 2 dichloroethane, acetonitrile, N, N dimethylformamide, dimethylsulfoxide, toluene, pyridine, methanol, ethanol, isopropanol, acetone, 2 butanone, hexane, heptane, pentane, ethyl acetate, and the like
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